James Pierce (1900–1983) was an American actor.
James Pierce may also refer to:
James Pieronnet Pierce (1825–1897), American pioneer entrepreneur in California James F. Pierce (1830–1905), American state senator from New York James Pierce (curler) (born 1963), American wheelchair Paralympian Jimmy Pierce, Marvel Comics Punisher superhero, first appearance 1993
See also James Pierce Jr. House, American historic home built in 1833 Todd James Pierce (born 1965), American novelist and short story writer James Peirce (c. 1674–1726), English dissenting minister James Pearce (disambiguation)