Ottolenghi is a toponymic surname of Jewish-Italian origin which was originally an Italianised form of Ettlingen. Notable people with the surname include:
Adolfo Ottolenghi (1885–1944), Jewish scholar and chief rabbi of Venice Emanuele Ottolenghi (born 1969), Italian political scientist Giuseppe Ottolenghi (1838–1904), Italian politician and military leader Les Ottolenghi, American casino executive Yotam Ottolenghi (born 1968), Israeli-British chef, restaurant owner and food writer
See also Rodrigues Ottolengui (1861-1937), American writer
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