Waterworth is a surname. Notable people with the surname include:
Alan William Waterworth (1931–2016), Lord Lieutenant of Merseyside Andrew Waterworth (born 1986), Northern Ireland footballer Edith Alice Waterworth (1873–1957), Australian welfare worker James Waterworth (1806–1876), English Catholic missionary priest Luke Waterworth (born 1996), Rugby League footballer Peter Waterworth (born 1957), British barrister and diplomat