Calflax is an unincorporated community in Fresno County, California. It is located northeast of Coalinga, at an elevation of 276 feet (84 m).

Calflax was established in the mid-1930s when irrigated flax and cotton fields were planted in the once-barren west San Joaquin Valley. Calflax originally had a school, store, and cotton gin. In 1959, the University of California West Side Research and Extension Center was established on the site of Calflax. A few scattered residences remain at the site today.

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