This is a list of software used to simulate the material and energy balances of chemical process plants. Applications for this include design studies, engineering studies, design audits, debottlenecking studies, control system check-out, process simulation, dynamic simulation, operator training simulators, pipeline management systems, production management systems, digital twins.

Software Developer Applications Operating System License URLAdvanced Simulation Library (ASL)Avtech ScientificProcess data validation and reconciliation, real-time optimization, virtual sensing and predictive controlWindows, Linux, FreeBSD, Macopen-source (AGPLv3)APMonitorAPMonitorMATLAB/Python/Julia-based data reconciliation, real-time optimization, dynamic simulation and nonlinear predictive controlWindows, Linuxopen-source (BSD-2-Clause)AprosFortum and VTT Technical Research Centre of FinlandDynamic process simulation for power plantsWindowsclosed-sourceASCENDASCENDDynamic process simulation, general purpose languageWindows, BSD, Linuxopen-source (GPLv2)Aspen Custom Modeler (ACM)Aspen TechnologyDynamic process simulationWindowsclosed-sourceAspen HYSYSAspen TechnologyProcess simulation and optimizationWindowsclosed-sourceAspen PlusAspen TechnologyProcess simulation and optimizationWindowsclosed-sourceASSETTKongsberg DigitalDynamic process simulationWindowsclosed-sourceBatchColumnFives ProSimSoftware for the Simulation and Optimization of batch distillation columnsWindowsclosed-sourceBATCHESBatch Process Technologies, Inc.Simulation of recipe driven multiproduct and multipurpose batch processes for applications in design, scheduling and supply chain managementLinuxclosed-sourceBatchReactorFives ProSimSimulation software dedicated to reactors in batch modeWindows closed-sourceBILCOCASPEOSoftware to simulate mass balances using a data reconciliation algorithmWindowsclosed-sourceBioSTEAMYoel Cortes-Pena & BioSTEAM Development GroupDesign, simulation, and costing of biorefineries under uncertaintyWindows, Mac, Linuxopen-source (BSD-3-Clause)CADSIM PlusAurel Systems Inc.Dynamic process simulator with CAD front end and process stream specification flexibilityWindowsclosed-sourceChromWorksYPSO-FACTOChromatographic process design, simulation & optimizationWindowsclosed-sourceCHEMCADChemstationsSoftware suite for process simulationWindowsclosed-sourceCHEMPROEPCONProcess Flow Simulation, Fluid Flow Simulation, & Process Equipment SizingWindows closed-sourceCycad ProcessCM SolutionsProcess simulation and drawing package for minerals and metallurgical fieldsWindowsclosed-sourceCycle-TempoAsimptoteThermodynamic analysis and optimization of systems for the production of electricity, heat and refrigerationWindowsclosed-sourceCOCO simulator + ChemSepAmsterCHEMSteady state process simulation based on CAPE-OPEN Interface StandardWindowsCoco License 3.4 D-SPICEKongsberg DigitalDynamic process simulationWindowsclosed-sourceDesign II for WindowsWinSim Inc.Process simulationWindowsclosed-sourceDistillation expert trainerATROperator training simulator for distillation processclosed-sourceDPSIMDirceu Nascimento / EPM – Empresa de Processos MineraisMineral process simulation, steady-state flowsheet simulation, material and water balances, particle-size distribution modelling, and dynamic process simulationWindowsfreeware (Static Module)DymolaDassault SystèmesModelica-based dynamic modelling and simulation softwareWindows, Linuxclosed-sourceDynoChemScale-up SystemsDynamic process simulation and optimizationWindowsclosed-sourceDYNSIMAVEVADynamic process simulationWindowsclosed-sourceDyssolDyssolTECDynamic flowsheet simulation of solids processesWindows, Linuxopen-source (BSD-3-Clause)DWSIMDaniel Medeiros, Gustavo León and Gregor ReichertProcess simulatorWindows, Linux, macOS, Android, iOSopen-source (GPLv3), freemiumEMSOALSOC ProjectModelling, simulation and optimisation, steady state and dynamic, equation oriented with open source modelsWindows, Linuxclosed-source (UI), open-source (library)EQ-COMPAmit KatyalVapor Liquid Equilibrium SoftwareSoftware-as-a-Serviceclosed-sourceFlowTranFlowTranTransient single phase pipeline simulationclosed-sourceGAMSGAMSGeneral Algebraic Modeling System (GAMS)Windows, Linux, Mac OS, Solarisclosed-sourcegPROMSPSE LtdAdvanced process simulation and modellingclosed-sourceHSC SimOutotec Oyj Advanced process simulation and modelling, Flowsheet simulationWindowsclosed-sourceHYD-PREDICAmit KatyalMultiphase flow assurance and hydrate modellingSoftware-as-a-Serviceclosed-sourceHYDROFLOTahoe Design SoftwarePiping System Design with Steady State AnalysisWindowsclosed-sourceIndiss Plus®CorysDynamic process simulator for hydrocarbons, chemicalsWindowsclosed-sourceICASKT-ConsortiumIntegrated Computer-Aided SystemWindowsclosed-sourceIDEASAndritz AutomationDynamic simulator for pulp, oil sands, potash, and hard rock miningWindowsclosed-sourceiiSE SimulatoriiSE companyEquation oriented chemical process simulator and optimizer Windows, Linuxclosed-sourceINOSIMInosim Software GmbHDiscrete-event dynamic simulation software for mixed batch-continuous processes in the chemical and pharmaceutical industryWindowsclosed-sourceINVIDESRheinmetall ElectronicsVisual, dynamic Process Simulation framework for power plants, pipeline systems, upstream, midstream and downstream oil & gas plants, renewable energy plants and hydrogen plantsWindowsclosed-sourceIPSE GOSimTech GmbHProcess simulation application that works in the browser, provides a visual flowsheet editor and supports online collaborationSoftware-as-a-Serviceclosed-sourceIPSEproSimTech GmbHVisual process simulation framework with ready-to-use model libraries for power systems, desalination, flue gas cleaning etc. and option to define own model librariesWindowsclosed-sourceITHACAElement ProcessGeneral purpose dynamic (continuous and discrete-event) chemical process simulator.Windowsfreemium, closed-sourceJADEGSE SystemsDynamic process simulationWindowsclosed-sourceJModelica.orgModelon ABProcess simulationWindows, Linux, macOSclosed-sourceK-SpiceKongsberg DigitalDynamic process simulationWindowsclosed-sourceLedaFlowKongsberg DigitalTransient multiphase pipeline simulationWindowsclosed-sourceLIBPFsimevoC++ Library for process flowsheetingLinux, Windows, macOSclosed-sourceMaximaLabs.ioMaximaLabsThe AI-Native Process Simulator — From Flowsheet to Live Digital TwinBrowser Anywhereclosed-sourceMETSIMMetsim InternationalGeneral-purpose dynamic and steady-state process simulation systemWindowsclosed-sourceModelon ImpactModelon ABGeneral-purpose, multi-domain dynamic and steady-state process and system simulation systemLinux (SaaS, on-prem), Windowsclosed-sourceMimic Simulation SoftwareMYNAH TechnologiesFirst-principles dynamic simulator built for software acceptance testing and operator training systemsWindowsclosed-sourceMobatec ModellerMobatecAdvanced Dynamic (Steady-State) Process Modelling EnvironmentWindowsclosed-sourceNAPCON ProsDSNeste Engineering Solutions OyDynamic process simulationWindowsclosed-sourceOLGASchlumbergerTransient multiphase pipeline simulationWindowsclosed-sourceOLI AnalyzerOLI Systems, Inc.Chemical phase equilibrium simulation featuring electrolytesWindowsclosed-sourceOmegalandOMEGA SimulationDynamic process simulationWindowsclosed-sourceOptiRampStatistics & Control, Inc.Real-time Process Simulation and Optimization, Multi variable Predictive ControlWindows closed-sourceOpenModelicaOpen-Source Modelica ConsortiumGeneral purpose simulationLinux, macOSopen-source (OSMC-PL 1.2)PD-PLUSDeerhaven Technical SoftwareSteady-State Modeling of Chemical, Petrochemical, and Refining ProcessesWindowsclosed-sourcePIPE-FLO ProfessionalEngineered Software Inc.Piping System Simulation and DesignWindowsclosed-sourcePIPEFLOSchlumbergerSteady state multiphase flowline simulationWindowsclosed-sourcePIPESIMSchlumbergerSteady state multiphase flowline simulationWindowsclosed-sourcePEL SuitePEL SoftwareSteady state process simulationWindowsclosed-sourcePetro-SIMKBC Advanced TechnologiesDynamic process simulationWindowsclosed-sourcePETROXPetrobrasIn-house steady state refining process simulatorWindowsclosed-sourceN/APower Plant Simulator & DesignerKED GmbHBasic Engineering and Dynamic process simulation for power plantsWindowsclosed-sourceProcess Engineering ToolS (PETS)Stratus Engineering, Inc.Process Engineering SoftwareWindowsclosed-sourceProcess StudioStamicarbonSimulation Suite for Modeling, Engineering & TrainingWindowsclosed-sourceProde PropertiesProde SoftwareThermodynamic Library, Properties of pure fluids and mixtures, Multi phase Equilibria + process simulationWindows, Linux, Androidclosed-sourceProde Process InterfaceProde SoftwareProcess simulation, optimization realtime controlWindowsclosed-sourceProMaxBryan Research & EngineeringProcess simulator capable of modeling oil & gas plants, refineries, and many chemical plantsWindowsclosed-sourceProPhyPlusFives ProSimThermodynamic calculation softwareWindowsclosed-sourceProSecFives ProSimSimulation software of brazed plate fin heat exchangersWindowsclosed-sourceProSim DACFives ProSimDynamic adsorption column simulation softwareWindowsclosed-sourceProSimPlusFives ProSimSoftware for steady-state simulation and optimization of processesWindowsclosed-sourceProSimPlus Python APIFives ProSimProcess simulator fully driven by PythonWindowsclosed-sourceProSimulatorSim InfosystemsProcess and Power plant simulation Windowsclosed-sourceProTreat / SulphurProOptimized Gas TreatingSteady state simulation of amine gas sweetening, glycol dehydration, modified Claus SRUs, tail gas clean-up, and post-combustion carbon capture processesWindowsclosed-sourcePRO/IIAVEVASteady state process simulationWindowsclosed-sourcePyomoSandia and UC DavisSteady state and dynamic process simulationAll Platformsopen-sourceROMeoAVEVAProcess optimizationWindowsclosed-sourceReaction LabScale-up SystemsChemist-oriented kinetic modeling and reaction optimizationWindowsclosed-sourceRecoVRVRTechIndustrial wastewater managementWindowsclosed-sourceREXOptienceReactor Optimization and Kinetic EstimationWindowsclosed-sourceAVEVA Process Simulation (former SimCentral)AVEVASteady state, Fluid flow and Dynamic process simulator.Windowsclosed-sourceSimCreateTSC SimulationReal time, first principle and generic operator training simulations, plant specific emulations and OPC for live plant connections.Windowsclosed-sourceSimulis ThermodynamicsFives ProSimMixture properties and fluid phase equilibria calculations add-inWindowsclosed-sourceSolidSim (Now in Aspen Plus)SolidSim Engineering GmbHFlowsheet simulation of solids processesWindowsclosed-sourceSPEEDUPAspen TechnologyDynamic process simulationUnix, Windowsclosed-sourceSuperPro DesignerIntelligenBatch and continuous process simulation.Windowsclosed-sourceSysCADKWA Kenwalt AustraliaSteady-state and dynamic process simulationWindowsclosed-sourceUniSim Design SuiteHoneywellProcess simulation and optimization Windowsclosed-sourceUniSim Competency SuiteHoneywellOperator Competency Management and TrainingWindowsclosed-sourceUSIM PACCASPEOSteady-state simulation and optimization of processesWindowsclosed-sourceVirtuosoWood PLCMultiphase dynamic process simulator for oil & gas productionWindowsclosed-sourceVMG SymmetrySchlumbergerSteady state simulation, dynamic process simulation, transient multiphase flowline simulationWindowsclosed-sourceWolfram SystemModelerWolfram ResearchModelica-based Dynamic multidomain modelling (mechanical, electrical, chemical)Windows, Mac, Linuxclosed-sourceXPSIMProcess Simulation ServicesSteady state and dynamic process simulation, transient multiphase pipeline simulatorWindowsclosed-source

See also Chemical engineering Process simulation Process engineering

References

Seader, J.D., Seider, W.D. and Pauls, A.C.: Flowtran Simulation – An Introduction, 2nd Edition, CACHE (1977). Douglas, J.M.: Conceptual Design of Chemical Processes, McGraw-Hill, NY, USA (1988).